Nanotechnology: Advanced science in ancient art

December 18, 2005

In the hip science of ultrasmall nanotechnology, fantastical future possibilities like rampaging nanorobots capture the most attention, but the first fruits of the field have been more mundane: tiny bits of mostly ordinary stuff that just sit there. Yet these bits—nanoparticles—gain wondrous new capabilities simply because they are so small.

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Self-assembled Nano-sized Probes Allow To See Tumors Through Flesh And Skin

February 18, 2005

Nano-sized particles embedded with bright, light-emitting molecules have enabled researchers to visualize a tumor more than one centimeter below the skin surface using only infrared light.

A team of chemists, bioengineers and medical researchers based at the University of Pennsylvania and the University of Minnesota has lodged fluorescent materials called porphyrins within the surface of a polymersome, a cell-like vesicle, to image a tumor within a living rodent. Their findings, which represent a proof of principle for the use of emissive polymersomes to target and visualize tumors, appear in the Feb. 7 online early edition of the Proceedings of the National Academy of Science.

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